The REOLUT node is consolidating early experimental, clinical and patient advocacy expertise from London, Cambridge and Manchester to build a UK-wide network that will work together to improve the diagnosis and care of patients with rare Lower Urinary Tract (LUT) disorders. In addition to forming a vibrant community of patients, researchers and clinicians that will train the future healthcare and academic leaders in rare LUT disorder research, this node will accelerate discoveries by:
1. Determining novel genetic causes of rare LUT disorders.
2. Understanding how genes are switched on and off in human LUT cells.
3. Optimising gene transfer into human LUT cells to potentially develop novel treatments.
